課程資訊
課程名稱
 量性研究方法於全球衛生之應用
Applied Quantitative Methods in Global Health 
開課學期
 112-2 
授課對象
 公共衛生學院  公共衛生學系  
授課教師
 張慶國 
課號
 DGH8002 
課程識別碼
 854ED0020 
班次
  
學分
 2.0 
全/半年
 半年 
必/選修
 選修 
上課時間
 星期三3,4(10:20~12:10) 
上課地點
 公衛203 
備註
 本課程以英語授課。歡迎碩士或大學部高年級學生選修與吳亞克合授
總人數上限：15人 
  
課程簡介影片
 
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課程概述

The aim of this course is to introduce advanced concepts about epidemiologic research design in the scope of global health with practical sessions involved and corresponding sophisticated statistical analysis methods. This course includes two parts: The first part on advanced biostatistical analysis methods will provide an overview of more complex methods for statistical analysis of practical processes and further inferences of quantitative research data. In the second part on advanced epidemiologic research methods, we will introduce cutting-edge methodologies of quantitative research design, causal inference, and the basis of scientific comparisons in related literature. Real-life examples from published articles in the field of global health will be illustrated and further elucidated in the course. 

課程目標
 At the end of the course, students will gain the following core knowledge and competencies:

1.Explain the role of quantitative and qualitative methods and sciences in describing and assessing a population’s health (D17-3)

2.Explain the social, political and economic determinants of health and how they contribute to population health and health inequities (D17-10)

3.Explain an ecological perspective on the connections among human health, animal health and ecosystem health (e.g. One Health) (D17-12)

4.Scrutinize and apply qualitative and quantitative methods to provide evidence-based solutions to global health problems considering cultural safety and diversity (DGH-2)

5.Design, implement, and evaluate theory-informed and evidence-based research programs in an academia or practice setting (DGH-3)

6.Recognize and analytically evaluate socioeconomic, environmental, behavioral, and biological determinants of population health (DGH-4) 
課程要求
 A preceding e-mail for calling sick before a lecture is essential. 
預期每週課後學習時數
 2 hours 
Office Hours
 另約時間 備註： Please email chinkuochang@ntu.edu.tw for making an appointment. 
指定閱讀
 To be uploaded on NTU COOL 
參考書目
 1.Epidemiologic Methods: Studying the Occurrence of Illness. 2nd Edition. Noel S. Weiss and Thomas D. Koepsell. Oxford University Press 2014.

2.Epidemiology: An Introduction. 2nd edition. Kenneth J. Rothman. Oxford University Press 2012.

3.Epidemiology (with STUDENT CONSULT Online Access). 5th edition. Leon Gordis. Elsevier Saunders 2013.

4.Modern Infectious Disease Epidemiology. 3rd edition. Johan Giesecke. CRC Press 2017.

5.R for Data Science. Garrett Grolemund and Hadley Wickham, https://r4ds.had.co.nz/

6.Statistical Rethinking: A Bayesian Course with Examples in R and Stan. 2nd edition. Richard McElreath. CRC Press 2020. https://www.youtube.com/watch?v=4WVelCswXo4&list=PLDcUM9US4XdNM4Edgs7weiyIguLSToZRI 
評量方式
(僅供參考)
    
針對學生困難提供學生調整方式
  
上課形式
 以錄音輔助, 以錄影輔助
作業繳交方式
考試形式
其他
課程進度
週次
日期
單元主題
Week 1
 2/21  Orientation (Biostats & Epi)
Linear regression (Biostats) 
Week 2
 2/28  National holiday – 228 Peace Memorial Day 
Week 3
 3/6  Fitting linear regression models (Biostats) 
Week 4
 3/13  Generalized linear models: logistic regression (Biostats) 
Week 5
 3/20  Generalized linear models: other regression models (Biostats) 
Week 6
 3/27  Causal inference and randomized experiments. Causal inference using regression on the treatment variable (Biostats) 
Week 7
 4/3  Bayesian statistics (Biostats) 
Week 8
 4/10  Midterm exam (Biostats: 40%) 
Week 9
 4/17  Power calculation and sample size estimation with practice sessions (Epi) 
Week 10
 4/24  Natural history of disease and disease surveillance (Epi)
Critical appraisal: Prevalence, trends, and associated social demographics of morbid obesity in survey (Epi) 
Week 11
 5/1  Special topic: Ecological study (Epi) 
Week 12
 5/8  Measuring the occurrence of disease (Epi)
Critical appraisal: Charcoal-burning suicide and media (Epi)* 
Week 13
 5/15  Critical appraisal: Deriving ethnic-specific BMI cutoff points for assessing diabetes risk (Epi) 
Week 14
 5/22  Critical appraisal: Exposure assessment in occupation epidemiology (Epi) 
Week 15
 5/29  Special topic: Genetic epidemiology and biobank (Epi) 
Week 16
 6/5  Final Exam in epidemiology (Epi: 40%)